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Peyona" is a caffeine citrate solution, indicated for the treatment of primary apnoea in preterm neonates. It can be administered either by slow intravenous infusion or orally.

Treatment with caffeine citrate should be initiated under the supervision of a physician experienced in neonatal intensive care. Treatment should be administered only in a neonatal intensive care unit in which adequate facilities are available for patient surveillance and monitoring.



The recommended dose regimen in previously untreated infants is a loading dose administered by slow intravenous infusion, followed by a maintenance dose that may be administered either intravenously or by oral administration through a nasogastric tube.